呼吸道軍團(tuán)菌快速檢測(cè)試紙（膠體金法）

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【公司名稱(chēng)】 廣州健侖生物科技有限公司
【】    楊永漢 
【】 
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有些染色體上除了初級(jí)縊痕以外，還有一個(gè)次級(jí)縊痕（secon－dary constriction），連上一個(gè)叫做隨體（salite）的遠(yuǎn)端染色體小段。次級(jí)縊痕的位置也是固定的。在細(xì)胞分裂將結(jié)束時(shí)，核內(nèi)出現(xiàn)一個(gè)到幾個(gè)核仁，核仁總是出現(xiàn)在次級(jí)縊痕的地方，所以次級(jí)縊痕也叫做核仁形成區(qū)（nucleolar organizer）如圖：著絲粒是有絲分裂或減數(shù)分裂中的染色體高度壓縮的一個(gè)區(qū)域，在此紡錘體纖維與其結(jié)合。復(fù)雜的DNA序列構(gòu)成了著絲粒。發(fā)育的面包酵母（啤酒酵母）的著絲粒長(zhǎng)度約為220個(gè)堿基對(duì)，并且通過(guò)多種與剩余DNA結(jié)合組蛋白有明顯區(qū)別的蛋白質(zhì)共同保護(hù)其免受限制性核酸內(nèi)切酶（簡(jiǎn)稱(chēng)限制酶）的消病毒。雖然著絲粒區(qū)域通過(guò)特殊的蛋自質(zhì)保護(hù)其免受限制性?xún)?nèi)切核酸酶的攻擊，但該區(qū)域投有核小體而且被去凝聚，這似乎說(shuō)明了在有絲分裂和減數(shù)分裂過(guò)程中著絲粒區(qū)域被高度縮窄原病毒。著絲粒的220對(duì)堿基序列兩側(cè)是限制性?xún)?nèi)切核酸酶敏感位點(diǎn)，該位點(diǎn)的功能也許是促進(jìn)DNA的斷裂，有助于染色單體在后期的相互分離。限制性?xún)?nèi)切核酸酶是一種在核酸內(nèi)特殊位點(diǎn)進(jìn)行切割的酶類(lèi)。
不同生物編輯
真核生物
真核生物的基病毒分布在許多染色體中，一般來(lái)講這些染色體在大小上有很大不同。與細(xì)菌染色體（由環(huán)狀DNA分子構(gòu)成）比較，真核染色體含有線性雙鏈DNA。DNA和多種類(lèi)型的相關(guān)蛋白質(zhì)構(gòu)成r染色體。真核染色體的結(jié)構(gòu)成分中并沒(méi)有RNA。
真核染色體可被不同程度的濃縮。zui低的濃縮結(jié)構(gòu)是伸展的核小體形式（extended nucleosome form）（圖3一la）。核小體是由近乎球狀的組蛋白形成的八聚體（histone）（H2a、H2b、H3和H4）和在其外圍繞兩圈的DNA所構(gòu)成。DNA的約200個(gè)堿基對(duì)圍繞著由組蛋白構(gòu)成的球形體。并有DNA的50個(gè)堿基對(duì)連接相鄰的核小體。雖然真核染色體伸展的核小體形式與細(xì)菌當(dāng)中看到的串珠樣的結(jié)構(gòu)相似，但是這些結(jié)構(gòu)可能并不相同。伸展的核小體形式存在于染色體將被復(fù)制的區(qū)域，或存在于與RNA分子合成有關(guān)的區(qū)域。

In addition to the primary marks on some chromosomes, there is a secon-dary constriction attached to a distal chromosome segment called the salite. Secondary marks the location is fixed. At the end of cell division, one to several nucleolus are present in the nucleus, and nucleolus always appears in the secondary lesion, so the secondary lesion is also called the nucleolar organizer. Particles are a region of highly compressed chromosomes during mitosis or meiosis, where spindle fibers bind. Complex DNA sequences constitute the centromere. The developed baker's yeast (Saccharomyces cerevisiae) has a centromere length of about 220 base pairs and is protected from restriction endonucleases by a number of proteins that differ significantly from the remaining DNA-binding histone Enzyme) of the virus. Although the centromeric region is intrinsically protected from the restriction endonuclease attack by a particular egg, the nucleosomes are cast and deaggregated in this region, which seems to indicate that during mitosis and meiosis The centromere region is highly constricted by the provirus. The centromeric 220 base pairs are flanked by restriction endonuclease-sensitive sites that may function to promote DNA cleavage and facilitate the subsequent separation of chromatids from one another. Restriction endonucleases are enzymes that cleave at specific sites within a nucleic acid.
Different creatures edit
Eukaryotes
Eukaryotic germ-line virus is distributed in many chromosomes, and in general these chromosomes vary widely in size. Eukaryotic chromosomes contain linear double-stranded DNA compared to bacterial chromosomes, which consist of circular DNA molecules. DNA and many types of related proteins make up the r chromosome. Eukaryotic chromosomes have no RNA in their structure.
Eukaryotic chromosomes can be concentrated to varying degrees. The lowest condensed structure is the extended nucleosome form (Figure 3 a la). The nucleosomes are composed of histones (H2a, H2b, H3 and H4) formed by nearly globular histones and DNAs that circle around their periphery. About 200 base pairs of DNA surround a spheroid of histones. And 50 base pairs of DNA connect adjacent nucleosomes. Although the eukaryotic chromosome stretches in a nucleosome-like form similar to the beaded-like structure seen in bacteria, these structures may not all be the same. Stretching nucleosomes exist in the area where the chromosomes are to be replicated or in the area associated with RNA molecule synthesis.